For example: Bayern Munich vs. MSV Duisburg. Handicap 0-2 (Duisburg is allowed a 2-goal head start). Even if Bayern really wins 1-0; you still win if you placed a handicap bet on Duisburg because the handicap makes the score 1-2 for the purposes of the bet.
Betting on the favored team (i.e., the team with a 2-goal handicap): If the favored team wins by a margin of exactly 2 goals, it results in a draw, and the bettor gets the stake back. If the favored team wins by a margin of 3 goals or more, the bet is a win, and the bettor receives the full winnings.