If you are in the early position or even the blinds, unless you have an excellent hand like pocket aces, kings, queens, ace king suited, or the bottom line - ace queen suited, you should fold all the other hands for the best result.
It's okay to fold big hands from time to time if your hand is vulnerable. Many poker players think they need to wait until later in the game to fold. However, if you can save yourself some money in a cash game, it's a good idea to fold earlier if things look dire.