Pluribus's self-play produces a strategy for the entire game offline, which we refer to as the blueprint strategy. Then during actual play against opponents, Pluribus improves upon the blueprint strategy by searching for a better strategy in real time for the situations in which it finds itself during the game.
The royal flush is a case of the straight flush. It can be formed 4 ways (one for each suit), giving it a probability of 0.000154% and odds of 649,739 : 1.